Program

  • Saturday, October 27, 2018

    09:00 am - 06:00 pm

    Workshops / satellite meetings / tutorials

    More information by clicking here 

  • Sunday, October 28, 2018

    08:30 am - 10:00 am
    Welcome
    10:00 am - 10:50 am Opening ceremony
    10:50 am - 11:50 am

    THE FAST AND THE FURIOUS: DISSECTING THE MECHANICS AND DYNAMICS OF RAPID CELL LOCOMOTION
    Julie Thériot, Seattle, USA

    11:50 am - 12:30 pm CLOCKS AND TIMERS IN DEVELOPMENT
    Andrew Oates, Lausanne, Switzerland
    12:30 pm - 02:00 pm Lunch
    02:00 pm - 03:30 pm Poster session
    03:30 pm - 04:00 pm Coffee break
    04:00 pm - 05:40 pm Three parallel sessions

    Multiscale Systems Biology

    DECIPHERING YEAST PHYSIOLOGY BY A MULTI‐SCALE FRAMEWORK INTEGRATING CELL CYCLE AND METABOLISM
    Matteo BARBERIS, Amsterdam, Netherlands

    ENABLING THE COMPARISON OF CONVENTIONAL AND NON-CONVENTIONAL WINEMAKING SACCHAROMYCES SPECIES WITH GENOME-SCALE MODELS
    David HENRIQUES, Vigo, Spain

    MULTI-SCALE MODELING REVEALS ANGIOGENESIS-INDUCED DRUG RESISTANCE IN BRAIN TUMOR AND PREDICTS A SYNERGISTIC DRUG COMBINATION TARGETING EGFR AND VEGFR
    Xiaoqiang SUN, Guangzhou, China

    A MULTI-SCALE SYSTEMS PHARMACOLOGY APPROACH FOR PERSONALIZING CANCER CHRONOTHERAPY
    Annabelle BALLESTA, Villejuif, France

    A MULTISCALE MATHEMATICAL MODEL OF NEURAL PROGENITOR DYNAMICS DURING THE DEVELOPMENT OF THE CEREBRAL CORTEX IN MICE
    Frederique CLEMENT, Palaiseau, France

    Developmental Systems Biology A

    COORDINATION OF DIFFERENT STEM CELL NICHES DURING HOMEOSTATIC GROWTH OF THE ADULT FISH EYE
    Erika TSINGOS, Eppelheim, Germany

    OCT4 IS REQUIRED AT THE M-G1 TRANSITION TO REESTABLISH CHROMATIN ACCESSIBILITY AT ENHANCERS IN PLURIPOTENT STEM CELLS
    Elias FRIMAN, Lausanne, Switzerland

    MITOTIC CHROMOSOME BINDING PREDICTS TRANSCRIPTION FACTOR DYNAMICS, TARGET SITE OCCUPANCY AND ABILITY TO MODIFY CHROMATIN ACCESSIBILITY
    Mahé RACCAUD, Lausanne, Switzerland

    MODELING CELL FATE SPECIFICATION DURING EARLY EMBRYONIC DEVELOPMENT IN MOUSE
    Didier GONZE, Bruxelles, Belgium

    NOISE-RESISTANT DEVELOPMENTAL REPRODUCIBILITY IN VERTEBRATE SOMITE FORMATION
    Honda NAOKI, Kyoto, Japan

    Systems Neurosciences

    MODELLING HYPERPOLARISATION-GATED SYNAPTIC PLASTICITY IN MOTOR LEARNING
    Melanie STEFAN, Edinburgh, United Kingdom

    HIERARCHICAL MODULARITY IN NEURAL NETWORKS
    Maria SERBAN, Copenhagen, Denmark

    SYSTEMS BIOLOGY APPLIED TO  POST-TRAUMATIC STRESS DISORDER TO STRATIFY INTO SUBTYPES
    Marti JETT, Washington, United States

    GENE NETWORKS, NEURON TYPES, AND BRAIN CIRCUITS UNDERLYING COMMON PSYCHIATRIC DISORDERS
    Dennis VITKUP, New York, United States

    ROBUSTNESS OF CONTROLLABILITY IN STRUCTURAL BRAIN NETWORKS
    Uiryong KANG, Daejeon, Korea, South

    05:50 pm - 06:30 pm James Ferrell, Stanford, USA
    06:30 pm Welcome cocktail
  • Monday, October 29, 2018

    08:30 am - 09:00 am Welcome
    09:00 am - 09:40 am

    SELF-ORGANISATION IN MOUSE DEVELOPMENT
    Takashi Hiiragi, Heidelberg, Germany

    09:40 am - 10:20 am AUXIN AND THE SELF-ORGANISATION OF PLANT FORM
    Ottoline Leyser, Cambridge, UK
    10:20 am - 10:50 am Coffee break
    10:50 am - 12:30 pm Three parallel sessions

    Methodological developments for Systems Biology A

    SMILES-BASED PREDICTION OF DRUG-TARGET INTERACTION BINDING AFFINITY
    Hakime OZTURK, ISTANBUL, Turkey

    USING DYNAMICAL REACTION NETWORK TO INFER DRUGS SELECTIVITY IN PHARMACOLOGY
    Romain YVINEC, Nouzilly, France

    DETECTING EPISTASIS USING RANDOM FOREST
    Corinna SCHMALOHR, Cologne, Germany

    ENZYME AND SUBSTRATE CONCENTRATIONS IN CELLULAR REACTION NETWORKS AT MAXIMAL GROWTH RATE
    Hugo DOURADO, Düsseldorf, Germany

    AUTOMATED STOCHASTIC PARAMETER ESTIMATION FOR EVENTS
    Min Kyoung ROH, Bellevue, United States

    Systems Medicine A

    LARGE-SCALE ANALYSIS OF HUMAN GENE EXPRESSION VARIABILITY ASSOCIATES HIGHLY VARIABLE DRUG TARGETS WITH LOWER DRUG EFFECTIVENESS AND SAFETY
    Eyal SIMONOVSKY, Beer Sheva, Israel

    MATHEMATICAL MODELLING OF E2F1 REPRESSION BY COOPERATIVE MICRORNA PAIRS IN THE CONTEXT OF ANTICANCER CHEMOTHERAPY RESISTANCE
    Xin LAI, Erlangen, Germany

    CONTROLLABILITY ANALYSIS OF THE CORE GENE REGULATORY NETWORK UNDERLYING EPITHELIAL-TO-MESENCHYMAL TRANSITION IN THE CONTEXT OF EPITHELIAL CANCER
    Juan MARTINEX, MEXICO CITY, Mexico

    PATIENT-SPECIFIC MODELLING OF THE NETWORK DYNAMICS INDUCED BY CHEMOTHERAPEUTIC DRUGS IN PRIMARY AND RELAPSED TUMOURS
    Dirk FEY, Dublin, Ireland

    OPTIMIZING DRUG COMBINATIONS FOR CANCER TREATMENT USING INTEGRATIVE NETWORK MODELLING
    Lan NGUYEN, Melbourne, Australia

    Modelling Networks and Circuits A

    E. COLI CAN SURVIVE STRESS BY NOISY GROWTH MODULATION
    Om PATANGE, Cambridge, United Kingdom

    THE TRIANGLE OF AGEING: A MODEL OF THE ACCUMULATION OF DAMAGED PROTEINS IN SACCHAROMYCES CEREVISIAE SHOWS HOW RETENTION ENABLES REPLICATIVE AGEING
    Johannes BORGQVIST, Gothenburg, Sweden

    EMERGENCE OF NON-GENETIC HETEROGENEITY IN METABOLIC REACTIONS
    Mona TONN, London, United Kingdom

    A GENOME-SCALE ANALYTICAL PREDICTION OF RIBOSOME, ENZYME, AND METABOLITE CONCENTRATIONS THAT MAXIMIZE BACTERIAL GROWTH RATE
    Hugo DOURADO, Düsseldorf, Germany

    FUNCTIONAL TOPOLOGY OF THE E COLI SMALL MOLECULE REGULATORY NETWORK
    Christian EULER, Toronto, Canada

    12:30 pm - 02:00 pm Lunch
    02:00 pm - 03:30 pm Poster session
    03:30 pm - 04:00 pm Coffee break
    04:00 pm - 05:40 pm Three parallel sessions

    Developmental Systems Biology B

    SIMULATING CELLULAR MOVEMENTS IN EARLY C. ELEGANS EMBRYOGENESIS
    Lidia YAMAMOTO, Leuven, Belgium

    MAKING AND ERASING PATTERNS IN THE TOOTH FIELD: LESSONS FROM EDAR DYNAMICS AND MATHEMATICAL MODELING
    Sophie PANTALACCI, Lyon, France

    3D MECHANICAL STRESS PATTERNING DURING FLOWER MORPHOGENESIS
    Olivier ALI, Lyon, France

    ENHANCER FUNCTION UNDERPINS ESSENTIAL PROPERTIES OF GENE REGULATORY NETWORKS FOR PATTERNING PRECISION
    Edgar HERRERA DELGADO, London, United Kingdom

    WET-TIP VERSUS DRY-TIP REGIMES OF OSMOTICALLY DRIVEN BILE FLOW IN THE LIVER
    Lutz BRUSCH, Dresden, Germany

    Multi-omics

    CAUSAL AND MECHANISTIC PAN-CANCER IMMUNE REGULATORY NETWORK DECIPHERED USING SYSTEMS GENETICS NETWORK ANALYSIS (SYGNAL)
    Chris PLAISIER, Tempe, United States

    DYNAMIC METABOLOMICS AND PHOSPHOPROTEOMICS REVEAL THAT INSULIN PRIMES THE ADIPOCYTE FOR GLUCOSE METABOLISM
    Katsuyuki YUGI, Tsurumi-ku, Yokohama, Japan

    EMERGENCE OF THE SPATIO-TEMPORAL REPLICATION PROGRAM: ROLE OF ORIGIN DISTRIBUTION HETEROGENEITY AND 3D CHROMATIN STRUCTURE
    Jean-Michel ARBONA, Lyon, France

    PENDA, A RANK-BASED METHOD FOR PERSONALIZED DIFFERENTIAL ANALYSIS: APPLICATION TO LUNG CANCER
    Magali RICHARD, La Tronche, France

    A HORMONE-REGULATED TRANSLATOME IN PRIMARY CELLS HIGHLIGHTS A POSITIVE FEEDBACK LOOP OF SIGNALING COMPONENTS OPERATING AT THE LEVEL OF TRANSLATION
    Pascale CRÉPIEUX, Nouzilly, France

    Evolutionary and Ecological Systems Biology

    QUANTIFYING SPATIOTEMPORAL DYNAMICS AND NOISE IN MICROBIOME STUDIES USING REPLICATE SAMPLING
    Brian JI, New York, United States

    HIGH-ORDER INTERACTIONS AND THE PREDICTABILITY OF FUNCTION IN MICROBIAL CONSORTIA
    Juan POYATOS, Madrid, Spain

    THE PERCOLATION OF METABOLISM AND BACTERIAL LIFESTYLE AND EVOLVABILITY
    German PLATA, New York, United States

    SYSTEMATIC EVALUATION OF CONDITIONAL GENE ESSENTIALITY CHANGES ACROSS GENETIC BACKGROUNDS IN SACCHAROMYCES CEREVISIAE
    Marco GALARDINI, Cambridge, United Kingdom

    NATURAL TRANSFORMATION: ACQUISITION AND REMOVAL OF MOBILE GENETIC ELEMENTS IN STOCHASTIC ENVIRONMENTS
    Gabriel CARVALHO, VILLEURBANNE, France

    05:50 pm - 06:30 pm QUANTITATIVE TRANSCRIPTION CONTROL MEDIATED BY SIGNALING NETWORK
    Mariko Okada, Osaka, Japan
  • Tuesday, October 30, 2018

    08:30 am - 09:00 am Welcome
    09:00 am - 09:40 am James Sharpe, Barcelona, Spain
    09:40 am - 10:20 am To be announced
    10:20 am - 10:50 am Coffee break
    10:50 am - 12:30 pm Three parallel sessions

    Single-cell Systems Biology

    NOISE AND CORRELATED GENE EXPRESSION IN A ONE-DIMENSIONAL ORGANISM
    Rinat ARBEL-GOREN, Rehovot, Israel

    EXPERIMENTAL AND THEORETICAL STUDY OF NUCLEAR DIFFUSION DYNAMICS OF TRANSCRIPTION FACTORS
    Nacho MOLINA, Strasbourg, France

    CELL-TO-CELL VARIABILITY IN THE ACTIVATION OF THE HEAT SHOCK RESPONSE
    Marie GUILBERT, Villeneuve d'Ascq, France

    SPATIALLY DISTRIBUTED NETWORK BETWEEN EGFR AND PHOSPHATASES OPTIMIZES GROWTH FACTOR SENSING AT CRITICALITY
    Aneta KOSESKA, Dortmund, Germany

    INTEGRATION OF GDF11 AND TGF-Β ON THE SMAD-SIGNALING PATHWAY - MODELLING POPULATION AVERAGE AND VARIABILITY BASED ON SINGLE CELL DATA
    Lorenz RIPKA, Mainz, Germany

    Quantitative Systems Physiology

    WHAT CAUSES METABOLIC OSCILLATIONS IN THE EUKARYOTIC CELL?
    Vakil TAKHAVEEV, Groningen, Netherlands

    NETWORK REDUCTION FOR GENOME SCALE METABOLIC MODELS
    Dipali SINGH, Dusseldorf, Germany

    INTERPLAY OF LOCAL AND GLOBAL REGULATORS IN PECTIN CATABOLISM DURING PLANT INFECTION BY DICKEYA DADANTII
    Shiny MARTIS B, Lyon, France

    STOCHASTICITY OF CELLULAR GROWTH: SOURCES, PROPAGATION AND CONSEQUENCES
    Andrea WEISSE, London, United Kingdom

    CIRCADIAN REGULATION OF CELL SIZE, DIVISION TIMING AND GROWTH IN CYANOBACTERIA
    Bruno MARTINS, Cambridge, United Kingdom

    Systems Biology for Synthetic Biology

    AN ARTIFICIAL CELL-CYCLE SYSTEM: HOW NETWORK STRUCTURES MODULATE THE CLOCK FUNCTIONS
    Qiong YANG, Ann Arbor, United States

    ON THE FEASIBILITY OF COMPLEX SYNTHETIC BIOLOGICAL CIRCUITS
    Carlos TOSCANO OCHOA, Barcelona, Spain

    PERCEPTIONS OF INHERENT SAFETY: A COMPARISON STUDY FROM THE BIOENGINEERING FIELD
    Britte BOUCHAUT, Delft, Netherlands

    OPTIMIZATION OF GENE EXPRESSION THROUGH COST-EFFECTIVE PROMOTER ARCHITECTURES
    Dvir SCHIRMAN, Revadim, Israel

    MODEL-BASED DESIGN OF ROBUST SYNTHETIC BIOLOGICAL CIRCUITS
    Claude LORMEAU, Zurich, Switzerland

    12:30 pm - 02:00 pm Lunch
    02:00 pm - 08:00 pm Cultural program
    08:00 pm Gala reception
  • Wednesday, October 31, 2018

    08:30 am - 09:00 am Welcome
    09:00 am - 09:40 am Ines Thiele, Luxembourg
    09:40 am - 10:20 am METABOLIC COORDINATION THROUGH METABOLITE-PROTEIN INTERACTIONS
    Uwe Sauer, Zürich, Switzerland
    10:20 am - 10:50 am Coffee break
    10:50 am - 12:30 pm Three parallel sessions

    Methodological developments for Systems Biology B

    SENSITIVE PARAMETERS AND TIPPING POINTS OF BIOCHEMICAL NETWORKS WITH POTENTIAL APPLICATIONS IN PRECISION MEDICINE
    Satya SAMAL, Aachen, Germany

    PARAMETER ESTIMATION IN DYNAMICAL MODELS FOR SYSTEMS BIOLOGY – THE DELICATE BALANCE BETWEEN IDENTIFIABILITY AND PREDICTIVITY
    Anne POUPON, Nouzilly, France

    THE PARAMETER EXPLOSION PROBLEM: EXTENDING THE SCOPE OF GRN MODELLING BY COMBINING REDUCED MODELS WITH EVOLUTIONARY COMPUTATION
    Ozgur AKMAN, Exeter, United Kingdom

    HYPERSPECTRAL CELL SOCIOLOGY ANALYSIS OF HISTOLOGICAL SPECIMENS
    Martial GUILLAUD, Vancouver, Canada

    FROM SYSTEMIC MODELS TO SYSTEMIC EPISTEMOLOGY IN CANCER RESEARCH
    Marta BERTOLASO, Rome, Italy

    Systems Medicine B

    CHARACTERIZATION OF DIFFERENT SEPSIS PHASES BY VIRTUAL INFECTION MODELING OF THE INNATE IMMUNE RESPONSE IN HUMAN WHOLE BLOOD
    Teresa LEHNERT, Jena, Germany

    AUTOMATED IMAGE ANALYSIS OF MAST CELL - DENDRITIC CELL INTERACTIONS REVEALS WEAPON TRANSFER IN IMMUNE SYSTEM
    Anna MEDYUKHINA, Jena, Germany

    NON-LINEAR MIXED EFFECTS MODELS TO STUDY INTER-INDIVIDUAL VARIABILITY IN CD8 T CELL IMMUNE RESPONSES IN MICE
    Chloe AUDEBERT, Villeurbanne, France

    MODELLING BISTABLE TUMOUR POPULATION DYNAMICS TO DESIGN EFFECTIVE TREATMENT STRATEGIES
    Chen-Hsiang YEANG, Taipei, Taiwan

    THE COMPLEX LIFE OF SMAD ISOFORMS DETERMINES GENE EXPRESSION IN HEPATOCELLULAR CARCINOMA
    Marcel SCHILLING, Heidelberg, Germany

    Modelling Networks and Circuits B

    INSTANTIATION OF PATIENT-SPECIFIC LOGICAL MODELS WITH MULTI-OMICS DATA ALLOWS CLINICAL STRATIFICATION OF PATIENTS
    Jonas BÉAL, Paris, France

    STRUCTURE-BASED KINETIC MODELLING REVEALS KINASE INHIBITOR COMBINATIONS TO OVERCOME ONCOGENIC RAS SIGNALLING
    Oleksii RUKHLENKO, Dublin, Ireland

    SYSTEMS NMR: SIMULTANEOUS QUANTITATIVE MONITORING OF RNA, PROTEIN, AND METABOLITE DYNAMICS FOR BIOMOLECULAR NETWORK ANALYSIS
    Yaroslav NIKOLAEV, Zurich, Switzerland

    ASSIGNING FUNCTION TO NATURAL ALLELIC VARIATION VIA DYNAMIC MODELING OF GENE NETWORK INDUCTION
    Daniel JOST, La Tronche, France

    INFERRING GENE REGULATORY NETWORKS USING SINGLE-CELL DATA: FROM MECHANISTIC MODELLING TO STATISTICS
    Ulysse HERBACH, Lyon, France

    12:30 pm - 02:00 pm Lunch
    02:00 pm - 03:30 pm Poster session
    03:30 pm - 04:00 pm Coffee break
    04:00 pm - 05:40 pm Three parallel sessions

    Methodological developments for Systems Biology C

    MIRNA SELECTION USING MIRNA NETWORK A PRIORI SHOWED IMPROVED RELIABILITY AND IDENTIFY FUNCTIONALLY RELATED MIRNAS
    Laurent GUYON, Grenoble, France

    OPTIMAL PART CHARACTERIZATION WITH SHARED CELLULAR RESOURCES
    Andras GYORGY, Abu Dhabi, United Arab Emirates

    A MULTIALGORITHMIC SIMULATOR FOR WHOLE-CELL BIOCHEMICAL MODELS
    Arthur GOLDBERG, New York, United States

    INTEGRATING FORMAL AND INFORMAL APPROACHES TO MODELING THE LIVING
    Fridolin GROSS, Milan, Italy

    MORPHEUS: A USER-FRIENDLY AND EXTENSIBLE SIMULATION FRAMEWORK FOR DECLARATIVE MODELLING IN MULTISCALE AND MULTICELLULAR SYSTEMS BIOLOGY
    Jörn STARRUSS, Dresden, Germany

    Systems Medicine C

    MACHINE LEARNING PIPELINE FOR PATHWAYS ANALYSIS WITH REVERSE PHASE MICROARRAY DATA OF NON-SMALL CELL LUNG CANCER CELL LINES AND DIFFERENT DRUGS
    Lorenzo TOMASSONI, Perugia, Italy

    PUTTING THE SQUEEZE ON RNA-SEQ DATA: MAPPING INDIVIDUALIZED GENETIC AND EPIGENETIC REGULATION IN COMPLEX DISEASES
    Michiel ADRIAENS, Maastricht, Netherlands

    THERAPEUTIC UNDERSTANDING OF HUMAN DOPAMINERGIC SYSTEM IN NEUROLOGICAL DISEASES - A SYSTEMS BIOLOGY APPROACH
    Avijit PODDER, New Delhi, India

    TRANSFORMING PHYSIOLOGICAL MODELS FROM MICE TO HUMANS - THE CASE OF IRON HOMEOSTASIS
    Pedro MENDES, Farmington, United States

    A CIRCADIAN METABOLOMICS ATLAS OF THE BODY UNDER CHRONIC NUTRIENT STRESS
    Dominik LUTTER, Neuherberg, Germany

    Modelling Networks and Circuits C

    TRANSCRIPTIONAL REGULATION OUT OF EQUILIBRIUM: THEORY AND EXPERIMENT
    Congxin LI, Heidelberg, Germany

    PRECISE ADAPTATION IN STEM CELL CONTROL
    Niklas KORSBO, Cambridge, United Kingdom

    AUTOMATED IMAGE ANALYSIS AND MODELING OF CALCIUM WAVES IN PLANT ROOTS
    Martin ZAUSER, Heidelberg, Germany

    PRINCIPLES THAT GOVERN COMPETITION OR CO-EXISTENCE IN RHO-GTPASE DRIVEN POLARIZATION IN THE BUDDING YEAST
    Jian-Geng CHIOU, Durham, United States

    CONTROLLING CELL FATE SPECIFICATION SYSTEM BASED ON NETWORK STRUCTURE
    Atsushi MOCHIZUKI, Kyoto, Japan

    05:50 pm - 06:30 pm IS PRECISION MEDICINE “OPEN”?
    Barbara Prainsack, Vienna, Austria
  • Thursday, November 1, 2018

    08:30 am - 09:00 am  Welcome
    09:00 am - 09:40 am  Angela DePace, Boston, USA
    09:40 am - 10:20 am  Nathalie Balaban, Jerusalem, Israel
    10:20 am - 10:50 am  Coffee break
    10:50 am - 11:50 am

    ADVENTURES WITH SINGLE MOLECULES IN BACTERIAL CELLS 
    Johan Elf, Uppsala, Sweden 

    11:50 am - 12:30 pm  Closing ceremony
    12:30 pm - 02:00 pm  Lunch